Spravato® Treatment in Tempe, AZ
SPRAVATO®, the only FDA-approved nasal spray for adults with treatment-resistant depression, reduces depression symptoms when two or more oral antidepressants haven’t worked. SPRAVATO® can be taken with or without an oral antidepressant.
Prefer to talk first?
Call or text 480-923-6200
Is Spravato® Right for Me?
Treatment-Resistant Depression Has Options
If you’ve tried antidepressants without meaningful relief, you’re not alone and you’re not out of options.
Spravato® (esketamine) may be appropriate if:
-
You’ve tried two or more antidepressants without adequate improvement
-
Depression continues to interfere with work, relationships, sleep, or daily life
-
Symptoms feel persistent, severe, or overwhelming
-
Your provider recommends advanced or next-step treatment options
Spravato® is FDA-approved for adults with:
-
Treatment-resistant depression (TRD)
-
Major depressive disorder (MDD) with acute suicidal thoughts or behaviors (when clinically appropriate)
📍 Spravato® treatment is available at our Tempe location
What Is Spravato® (Esketamine)?
FDA-Approved Esketamine Therapy for Depression
Spravato® is a prescription nasal spray containing esketamine, a medication derived from ketamine and specifically approved by the FDA for depression.
Unlike traditional antidepressants that primarily affect serotonin, Spravato® works on the brain’s glutamate system, which plays a key role in mood regulation, neuroplasticity, and stress response.
Many patients pursue Spravato® after standard medications haven’t worked or haven’t worked well enough.
Key points about Spravato®:
-
FDA-approved and evidence-based
-
Administered only in a certified medical setting
-
Part of the Spravato® REMS safety program
-
Not taken at home
-
Requires post-dose monitoring for safety
Spravato® is not a cure, but for some patients, it can provide meaningful symptom relief when other options have failed.
What to Expect at Each Visit
Spravato® treatment is structured, supervised, and designed with patient safety in mind.
A typical Spravato® appointment includes:
-
Check-in & vitals
A brief medical and mental health assessment before treatment -
Self-administration
You administer the nasal spray under clinician supervision -
Comfortable observation period
You relax in a calm, monitored environment -
Required monitoring (minimum 2 hours)
This is mandated by the FDA and Spravato® REMS program -
Discharge planning
You must have a ride home, driving is not permitted the same day
Treatment Schedule
-
Induction phase: Often twice weekly for the first 4 weeks
-
Maintenance phase: Weekly or every other week (individualized)
Your exact plan is determined by your provider based on symptoms, response, and safety considerations.
Safety, Monitoring & the Spravato® REMS Program
Why Spravato® Is Only Offered In-Office
Spravato® has important safety considerations, including risks of:
-
Sedation
-
Dissociation
-
Increased blood pressure
-
Abuse or misuse potential
-
Suicidal thoughts or behaviors
Because of these risks, Spravato® is available only through the Spravato® REMS (Risk Evaluation and Mitigation Strategy) program.
This means:
-
Treatment must occur in a certified medical clinic
-
Patients must be monitored for at least 2 hours
-
Transportation home is required
-
Ongoing assessment is part of care
At Alevea Mental Health, safety and compliance are non-negotiable and central to how we deliver Spravato® care.
Benefits of Spravato® Treatment
Why Patients Explore Esketamine Therapy
While individual results vary, patients pursue Spravato® because it:
-
Offers a different mechanism of action than traditional antidepressants
-
May provide faster symptom improvement for some patients
-
Is supported by clinical trials and FDA approval
-
Is delivered in a structured, medically supervised setting
-
Can be part of a broader, personalized mental health plan
Spravato® is often considered when depression feels stuck, chronic, or unresponsive to standard treatments.
Spravato® vs Ketamine Therapy
What’s the Difference?
Patients often ask how Spravato® compares to ketamine infusions.
Spravato®:
-
FDA-approved for depression
-
Esketamine nasal spray
-
Provided under strict REMS requirements
-
Insurance coverage is available
-
Administered only in certified clinics
Ketamine infusions:
-
FDA off-label for mental health
-
IV administration
-
Not covered by insurance
-
Same strict safety protocols
During your consultation, we’ll help you understand which options may be appropriate for your specific situation.
Is SPRAVATO® Covered By Insurance?
Many insurance plans do cover Spravato®, though prior authorization is often required.
Coverage depends on:
-
Diagnosis (e.g., TRD)
-
Documented medication history
-
Individual plan benefits
Our team can help:
-
Verify potential coverage
-
Explain the authorization process
-
Clarify visit frequency and expectations
📞 Questions about cost or insurance? Call or text 480-923-6200.
👉 Check My Insurance for Spravato
Why Choose Alevea Mental Health?
Local, Evidence-Based Spravato® Care in Arizona
Patients choose Alevea Mental Health because we offer:
-
Spravato® treatment in Tempe
-
Clinician-led evaluation and treatment planning
-
Calm, supportive in-office environment
-
Clear communication and realistic expectations
-
Focus on safety, dignity, and patient experience
We believe advanced treatments should be delivered thoughtfully never rushed, not transactional.
Take the Next Step
If depression hasn’t responded to traditional treatments, Spravato® may be an option worth exploring.
Our team is here to answer questions, review eligibility, and help you decide whether this treatment fits your needs.
Easily schedule a Spravato Consult with one of our amazing providers online or tex/call us!
Prefer to talk first?
Call or text 480-923-6200